Vitamin D Deficiency Ups Risk of Multiple Sclerosis, Arthritis, Diabetes, and Cancers
August 26, 2010
Kyriaki (Sandy) Venetis Just about the only time most of us notice vitamin D is when we see it on a milk cartoon and even then we’re oblivious to it, but growing research says that maybe we shouldn’t be. A study published earlier this week in Genome Research has mapped out the points where vitamin D interacts with our DNA. It also looked at how a deficiency of the vitamin in the body can increase the risk of a number of chronic conditions and illnesses.

The researchers found 2,776 sites along a person’s genetic code that are activated by vitamin D and influence what proteins are made. These sites are unusually concentrated near a number of genes associated with the susceptibility to autoimmune conditions, including:
- Multiple sclerosis
- Rheumatoid arthritis
- Crohn’s disease
- Lupus
- Rickets
- Cancers of the breast, colorectal, pancreatic, and chronic lymphocytic leukemia
Deficiencies in vitamin D can also contribute to lower insulin production, which can exacerbate type-1 diabetes, sometimes called juvenile diabetes or insulin-dependent diabetes. This is a chronic condition where the pancreas produces little or no insulin.






